Stent Selection in Complex Coronary Interventions: Thinking Complex?

Absorb Bioresorbable Vascular Scaffold in Complex Coronary Bifurcation Interventions

Treatment of coronary bifurcation lesions is common in everyday practice and accounts for ≤20% of all percutaneous coronary interventions. The treatment of these lesions with drug-eluting stents, especially when a double-stent technique is used, remains challenging and is associated with a lower procedural success and a higher rate of long-term adverse cardiac events such as stent restenosis an...

Complex systems: Network thinking

In this article, I discuss some recent ideas in complex systems on the topic of networks, contained in or inspired by three recent complex systems books. The general science of networks is the subject of Albert-Lazlo Barabási’s Linked [A.-L. Barabási, Linked: The New Science of Networks, Perseus, New York, 2002] and Duncan Watts’ Six Degrees [D. Watts, Six Degrees: The Science of a Connected Ag...

Thinking Systemically About Complex Systems

Complex interventions or complex systems? Implications for health economic evaluation.

Health researchers commonly use the notion of complexity to indicate the problems faced in evaluating the effectiveness of many non-drug interventions.1-3 However, although it is rarely delineated, complexity has two meanings. In the first it is a property of the intervention, and in the second it is a property of the system in which the intervention is implemented. We examine the implications ...

Testing protocols in the intensive care unit: complex trials of complex interventions for complex patients.